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Reasons you or someone you know may struggle with the holiday blues include trauma, grief, or unpleasant memories the loss of a loved one difficult family relationships or the end of a relationship anxiety or depression loneliness or social isolation pressure to participate in social gatherings and festivities financial stress the anticipation of awkward or uncomfortable topics of conversation unrealistic expectations to have the perfect holiday season a lack of holiday spirit During the holidays, it is also important to look out for and be respectful of those struggling with mental health and/or substance use disorders